Two sample MR report
KANSL1-AS1_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0512896 | 0.3373068 | 0.9039339 |
| Weighted median | 3 | 0.0213348 | 0.0124762 | 0.0872590 |
| Inverse variance weighted | 3 | 0.0202972 | 0.0096372 | 0.0351931 |
| Simple mode | 3 | 0.0222770 | 0.0127847 | 0.2235487 |
| Weighted mode | 3 | 0.0222210 | 0.0131403 | 0.2328955 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0345716 | 1 | 0.8524962 |
| Inverse variance weighted | 0.0796502 | 2 | 0.9609575 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0610807 | 0.287686 | 0.8668124 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.11e-05 | 0 | TRUE | 0.5968445 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
